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Assay Detail

CHEMBL818692

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Binding
Evaluated for the binding affinity towards Vasopressin V1a receptor in rat liver membrane using [3H]AVP as radioligand
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Liver
Subcellular Membrane
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Vasopressin V1a receptor (CHEMBL2868)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

N-Methylbenzanilide derivatives as a novel class of selective V(1A) receptor antagonists.
Kakefuda A, Tsukada J, Kusayama T, Tahara A, Tsukamoto S.
Bioorg Med Chem Lett (2002) 12 : 229 -232
PubMed 11755361 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.63 7.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL296908 1 7.63

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL296908 Ki = 23.5 nM 7.63