Assay Detail
Functional
CHEMBL818772
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Ability to inhibit mGluR2-alpha induced cAMP formation was determined at BHK cells at 100 Micro M Concentration
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mesocricetus auratus |
| Cell Type | BHK |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked metabotropic glutamate receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.32 | 4.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL444589 | — | — | 1 | 4.32 |
| CHEMBL299683 | — | — | 1 | - |
| CHEMBL328984 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL444589 | — | IC50 | = | 48000.0 | nM | 4.32 |
| CHEMBL299683 | — | IC50 | = | 340000.0 | nM | - |
| CHEMBL328984 | — | IC50 | = | 577000.0 | nM | - |