Assay Detail
Functional
CHEMBL818997
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of lipopolysaccharide stimulated TNF-alpha release in human whole blood
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Blood |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.50 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL848 | LENALIDOMIDE | 4.0 | 1 | 7.00 |
| CHEMBL43855 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL848 | LENALIDOMIDE | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL43855 | — | IC50 | = | 100000.0 | nM | 4.00 |