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Assay Detail

CHEMBL819243

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for its anti tubulin activity
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Tubulin alpha chain (CHEMBL3658)
Type SINGLE PROTEIN
Organism Sus scrofa

Publication

Design and synthesis of curacin a analogs with varied side chain structures
Nishikawa A, Shirai R, Koiso Y, Hashimoto Y, Iwasaki S
Bioorg Med Chem Lett (1997) 7 : 2657 -2660
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.60 5.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL89138 CURACIN A 1 5.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL89138 CURACIN A IC50 = 2500.0 nM 5.60