Assay Detail
Functional
CHEMBL819244
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Compound was tested for inhibitory activity against tubulin polymerization
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design and synthesis of curacin a analogs with varied side chain structures
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.60 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL89138 | CURACIN A | — | 1 | 5.60 |
| CHEMBL91881 | — | — | 1 | - |
| CHEMBL314904 | — | — | 1 | - |
| CHEMBL313796 | — | — | 1 | - |
| CHEMBL328684 | — | — | 1 | - |
| CHEMBL327770 | — | — | 1 | - |
| CHEMBL88531 | — | — | 1 | - |
| CHEMBL89124 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL89138 | CURACIN A | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL91881 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL314904 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL313796 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL328684 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL327770 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL88531 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL89124 | — | IC50 | > | 50000.0 | nM | - |