Assay Detail
Binding
CHEMBL819305
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of c-AMP dependent kinase (PKA) catalytic subunit
10
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
New hexahydroxybiphenyl derivatives as inhibitors of protein kinase C.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.65 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL266951 | — | — | 1 | 4.82 |
| CHEMBL217600 | — | — | 1 | 4.72 |
| CHEMBL61518 | — | — | 1 | 4.68 |
| CHEMBL294037 | — | — | 3 | 4.54 |
| CHEMBL292719 | — | — | 1 | - |
| CHEMBL305099 | — | — | 1 | - |
| CHEMBL59451 | — | — | 1 | - |
| CHEMBL507308 | PUNICAFOLIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL266951 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL217600 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL61518 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL294037 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL294037 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL292719 | — | IC50 | > | 218000.0 | nM | - |
| CHEMBL305099 | — | IC50 | > | 218000.0 | nM | - |
| CHEMBL294037 | — | IC50 | > | 218000.0 | nM | - |
| CHEMBL59451 | — | IC50 | > | 218000.0 | nM | - |
| CHEMBL507308 | PUNICAFOLIN | IC50 | > | 218000.0 | nM | - |