Assay Detail
Binding
CHEMBL819402
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of human T-cells voltage-gated potassium channel subunit Kv1.3
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | T-cell |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Potassium voltage-gated channel subfamily A member 3 (CHEMBL4633) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The SAR of UK-78,282: A novel blocker of human T cell Kv1.3 potassium channels
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.70 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL9653 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL9653 | — | IC50 | = | 200.0 | nM | 6.70 |