Assay Detail
Functional
CHEMBL820107
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Antiviral activity evaluated against Varicella Zoster virus (YS)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel bicyclic furanopyrimidines with dual anti-VZV and -HCMV activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.44 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3143173 | — | — | 1 | 7.70 |
| CHEMBL3143172 | — | — | 1 | 7.52 |
| CHEMBL3143167 | — | — | 1 | 7.52 |
| CHEMBL3143171 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3143173 | — | EC50 | = | 20.0 | nM | 7.70 |
| CHEMBL3143172 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL3143167 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL3143171 | — | EC50 | = | 100.0 | nM | 7.00 |