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Assay Detail

CHEMBL820244

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity towards rat Vasopressin V2 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Vasopressin V2 receptor (CHEMBL3766)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Novel design of nonpeptide AVP V(2) receptor agonists: structural requirements for an agonist having 1-(4-aminobenzoyl)-2,3,4, 5-tetrahydro-1H-1-benzazepine as a template.
Kondo K, Ogawa H, Shinohara T, Kurimura M, Tanada Y, Kan K, Yamashita H, Nakamura S, Hirano T, Yamamura Y, Mori T, Tominaga M, Itai A.
J Med Chem (2000) 43 : 4388 -4397
PubMed 11087564 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.82 6.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL340893 1 6.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL340893 IC50 = 150.0 nM 6.82