Vasopressin V2 receptor · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt Q00788. Use UniProt Q00788 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q00788 as the stable identity anchor, then attach disease evidence before program review.
Vasopressin V2 receptor
Review this target as Vasopressin V2 receptor, mapped to UniProt Q00788. Sequence length is 371 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Vasopressin V2 receptor as ChEMBL target CHEMBL3766, mapped to UniProt Q00788. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Vasopressin V2 receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q00788 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Vasopressin V2 receptor |
| UniProt Accession | Q00788 |
| Component Type | Protein |
| Sequence Length | 371 aa |
Vasopressin V2 receptor
Review this target as Vasopressin V2 receptor, mapped to UniProt Q00788. Sequence length is 371 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4468523 | 10.7 | EC50 | 0.02 | Preclinical |
| CHEMBL1429 | 10.52 | EC50 | 0.03 | Approved |
| CHEMBL4539370 | 10.3 | EC50 | 0.05 | Preclinical |
| CHEMBL375324 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL435323 | 9.59 | Ki | 0.26 | Preclinical |
| CHEMBL1429 | 9.52 | Ki | 0.3 | Approved |
| CHEMBL221436 | 9.52 | Ki | 0.3 | Preclinical |
| CHEMBL506235 | 9.4 | Ki | 0.4 | Preclinical |
| CHEMBL373742 | 9.35 | Ki | 0.45 | Approved |
| CHEMBL49429 | 9.3 | IC50 | 0.5 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 30 | 133 | 7.0 |
| tissue-based format | 15 | 63 | 6.5 |
| assay format | 9 | 201 | 5.8 |
| cell membrane format | 4 | 34 | 7.5 |
| cell-based format | 2 | 2 | 8.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 5 | 0 | — |
| cell-based format | 4 | 10 | 8.3 |
| organism-based format | 4 | 13 | 7.3 |
| cell membrane format | 2 | 0 | — |