Assay Detail
Functional
CHEMBL820409
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In vitro agonist activity, increased [Ca2+] influx, at vanilloid receptor of rat dorsal root ganglia
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
N-4-Substituted-benzyl-N'-tert-butylbenzyl thioureas as vanilloid receptor ligands: investigation on the role of methanesulfonamido group in antagonistic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.34 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL294199 | CAPSAICIN | 4.0 | 1 | 7.52 |
| CHEMBL165129 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL294199 | CAPSAICIN | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL165129 | — | EC50 | = | 7000.0 | nM | 5.16 |