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Assay Detail

CHEMBL820420

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Affinity for c-Jun N-terminal kinase 3
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Mitogen-activated protein kinase 10 (CHEMBL2637)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Fragment-based drug discovery.
Erlanson DA, McDowell RS, O'Brien T.
J Med Chem (2004) 47 : 3463 -3482
PubMed 15214773 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.52 6.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL117120 1 6.14
CHEMBL117121 1 4.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL117120 Ki = 720.0 nM 6.14
CHEMBL117121 Ki = 13000.0 nM 4.89