Assay Detail
Functional
CHEMBL820863
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Concentration required for 50% inhibition of growth in normal human lung fibroblast (WI-38 cell line) cell line was determined
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | WI-38 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and anticancer evaluation of vitamin K(3) analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.22 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL93755 | — | — | 1 | 5.30 |
| CHEMBL92659 | — | — | 1 | 5.13 |
| CHEMBL93699 | — | — | 1 | - |
| CHEMBL91008 | — | — | 1 | - |
| CHEMBL90140 | — | — | 1 | - |
| CHEMBL329399 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL93755 | — | IC50 | = | 5060.0 | nM | 5.30 |
| CHEMBL92659 | — | IC50 | = | 7370.0 | nM | 5.13 |
| CHEMBL93699 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL91008 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL90140 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL329399 | — | IC50 | > | 10000.0 | nM | - |