Assay Detail
Functional
CHEMBL820968
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The concentration required to inhibit the growth of viral plaques by 50% of control in plaque reduction assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Modifications on the heterocyclic base of acyclovir: syntheses and antiviral properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | 7.00 |
| CHEMBL175683 | — | — | 1 | - |
| CHEMBL174837 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL175683 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL174837 | — | IC50 | = | 129000.0 | nM | - |