Assay Detail
Binding
CHEMBL821092
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards human Vasopressin V1b receptor
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and characterization of fluorescent antagonists and agonists for human oxytocin and vasopressin V(1)(a) receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 11 | 6.89 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1790729 | — | — | 1 | 7.28 |
| CHEMBL1790717 | — | — | 1 | 7.18 |
| CHEMBL1790719 | — | — | 1 | 7.06 |
| CHEMBL1790718 | — | — | 1 | 6.91 |
| CHEMBL1790720 | — | — | 1 | 6.90 |
| CHEMBL1790728 | — | — | 1 | 6.82 |
| CHEMBL1790711 | — | — | 1 | 6.55 |
| CHEMBL1790721 | — | — | 1 | 6.41 |
| CHEMBL1790722 | — | — | 1 | - |
| CHEMBL1790713 | — | — | 1 | - |
| CHEMBL1790712 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1790729 | — | Ki | = | 53.0 | nM | 7.28 |
| CHEMBL1790717 | — | Ki | = | 66.0 | nM | 7.18 |
| CHEMBL1790719 | — | Ki | = | 87.0 | nM | 7.06 |
| CHEMBL1790718 | — | Ki | = | 124.0 | nM | 6.91 |
| CHEMBL1790720 | — | Ki | = | 126.0 | nM | 6.90 |
| CHEMBL1790728 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL1790711 | — | Ki | = | 282.0 | nM | 6.55 |
| CHEMBL1790721 | — | Ki | = | 393.0 | nM | 6.41 |
| CHEMBL1790722 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL1790713 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1790712 | — | Ki | > | 10000.0 | nM | - |