Assay Detail
Binding
CHEMBL821348
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for inhibition constant at V2 receptor of rat kidney membrane
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A new series of photoactivatable and iodinatable linear vasopressin antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.64 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL424905 | — | — | 1 | 8.80 |
| CHEMBL405440 | — | — | 1 | 8.52 |
| CHEMBL412192 | — | — | 1 | 8.10 |
| CHEMBL441195 | — | — | 1 | 8.00 |
| CHEMBL265048 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL424905 | — | Ki | = | 1.6 | nM | 8.80 |
| CHEMBL405440 | — | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL412192 | — | Ki | = | 8.0 | nM | 8.10 |
| CHEMBL441195 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL265048 | — | Ki | = | 16000.0 | nM | 4.80 |