Assay Detail
Functional
CHEMBL821852
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration producing half maximal aggregation of pigment granules in the centre of the melanophore isolated from the neural crest of Xenopus laevis embryos was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | frog |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Mapping the melatonin receptor. 1. the 5-methoxyl group of melatonin is not an essential requirement for biological activity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.23 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL15013 | — | — | 1 | 7.30 |
| CHEMBL15318 | — | — | 1 | 7.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL15013 | — | EC50 | = | 50.0 | nM | 7.30 |
| CHEMBL15318 | — | EC50 | = | 70.0 | nM | 7.16 |