Assay Detail
Functional
CHEMBL822221
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Inhibition of CCK-8-stimulated amylase release from pancreatic acinar cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
beta-Turned dipeptoids as potent and selective CCK(1) receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.58 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13577 | — | — | 1 | 8.92 |
| CHEMBL9506 | DEVAZEPIDE | 2.0 | 1 | 8.60 |
| CHEMBL276837 | — | — | 1 | 8.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13577 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL9506 | DEVAZEPIDE | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL276837 | — | IC50 | = | 6.0 | nM | 8.22 |