Assay Detail
Binding
CHEMBL822409
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Inhibition of I-iodocyanopindolol binding to human beta 2 adrenergic receptors
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
(4-Piperidin-1-yl)phenyl amides: potent and selective human beta(3) agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 6.15 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL36060 | — | — | 1 | 10.00 |
| CHEMBL12998 | L-755507 | — | 1 | 6.80 |
| CHEMBL32599 | — | — | 1 | 6.32 |
| CHEMBL285881 | — | — | 1 | 5.47 |
| CHEMBL35282 | — | — | 1 | 5.44 |
| CHEMBL36568 | — | — | 1 | 4.94 |
| CHEMBL32590 | — | — | 1 | 4.10 |
| CHEMBL418600 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL36060 | — | Ki | = | 0.1 | nM | 10.00 |
| CHEMBL12998 | L-755507 | Ki | = | 160.0 | nM | 6.80 |
| CHEMBL32599 | — | Ki | = | 480.0 | nM | 6.32 |
| CHEMBL285881 | — | Ki | = | 3400.0 | nM | 5.47 |
| CHEMBL35282 | — | Ki | = | 3600.0 | nM | 5.44 |
| CHEMBL36568 | — | Ki | = | 11600.0 | nM | 4.94 |
| CHEMBL32590 | — | Ki | = | 79200.0 | nM | 4.10 |
| CHEMBL418600 | — | Ki | > | 100000.0 | nM | - |