Assay Detail
Binding
CHEMBL822473
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro activity to increase cAMP levels in Chinese hamster ovary (CHO) cells expressing the cloned human beta 1 Adrenergic receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
(4-Piperidin-1-yl)phenyl amides: potent and selective human beta(3) agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.50 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL12998 | L-755507 | — | 1 | 6.48 |
| CHEMBL35500 | — | — | 1 | 5.70 |
| CHEMBL284311 | — | — | 1 | 4.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL12998 | L-755507 | EC50 | = | 330.0 | nM | 6.48 |
| CHEMBL35500 | — | EC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL284311 | — | EC50 | = | 48700.0 | nM | 4.31 |