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Assay Detail

CHEMBL822659

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of ADP-induced platelet aggregation of human PRP without pig aortal microsomes (PAM)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Tissue Aorta
Confidence 1 — Organism
Curated By Expert

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.
Martinez GR, Walker KA, Hirschfeld DR, Bruno JJ, Yang DS, Maloney PJ.
J Med Chem (1992) 35 : 620 -628
PubMed 1311763 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.01 4.01

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL283656 DAZMEGREL 2.0 1 4.01

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL283656 DAZMEGREL IC50 = 97000.0 nM 4.01