Assay Detail
Functional
CHEMBL824150
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Compound was tested in vitro for inhibitory activity against human FKBP
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Studies on an immunosuppressive macrolactam, ascomycin: synthesis of a C-33 hydroxyl derivative.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.34 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL172542 | — | — | 1 | 8.92 |
| CHEMBL8597 | ASCOMYCIN | — | 1 | 8.69 |
| CHEMBL367449 | — | — | 1 | 7.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL172542 | — | IC50 | = | 1.21 | nM | 8.92 |
| CHEMBL8597 | ASCOMYCIN | IC50 | = | 2.06 | nM | 8.69 |
| CHEMBL367449 | — | IC50 | = | 39.2 | nM | 7.41 |