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Assay Detail

CHEMBL824231

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro cytotoxic activity against human colon adenocarcinoma (HT-29)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents.
Antonini I, Polucci P, Magnano A, Gatto B, Palumbo M, Menta E, Pescalli N, Martelli S.
J Med Chem (2003) 46 : 3109 -3115
PubMed 12825949 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.30 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL105362 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL105362 IC50 = 500.0 nM 6.30