Assay Detail
Functional
CHEMBL826401
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against MeVo melanoma cell line
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and cytotoxic evaluation of novel spirohydantoin derivatives of the dihydrothieno[2,3-b]naphtho-4,9-dione system.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.35 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL178282 | — | — | 1 | 6.60 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL178282 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 820.0 | nM | 6.09 |