Assay Detail
Functional
CHEMBL826418
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In vitro inhibition of ADP-induced platelet aggregation in dog platelet rich plasma
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Canis lupus familiaris |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Discovery of new diphenyloxazole derivatives containing a pyrrolidine ring: orally active prostacyclin mimetics. Part 2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.00 | 6.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL190497 | — | — | 1 | 6.11 |
| CHEMBL132589 | — | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL190497 | — | IC50 | = | 780.0 | nM | 6.11 |
| CHEMBL132589 | — | IC50 | = | 1300.0 | nM | 5.89 |