Assay Detail
Functional
CHEMBL826577
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Potency of compound in glycogen accumulation in L6 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | L6 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
4-Acylamino-6-arylfuro[2,3-d]pyrimidines: potent and selective glycogen synthase kinase-3 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.27 | 6.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL182419 | — | — | 1 | 6.41 |
| CHEMBL361196 | — | — | 1 | 6.13 |
| CHEMBL183038 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL182419 | — | EC50 | = | 390.0 | nM | 6.41 |
| CHEMBL361196 | — | EC50 | = | 740.0 | nM | 6.13 |
| CHEMBL183038 | — | EC50 | > | 10000.0 | nM | - |