Assay Detail
Binding
CHEMBL827137
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Binding affinity against Alpha1 adrenergic receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Aminotriazine 5-HT7 antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.74 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL182937 | — | — | 1 | 7.00 |
| CHEMBL413049 | — | — | 1 | 6.70 |
| CHEMBL182174 | — | — | 1 | 6.52 |
| CHEMBL182418 | — | — | 1 | - |
| CHEMBL180086 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL182937 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL413049 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL182174 | — | Ki | = | 300.0 | nM | 6.52 |
| CHEMBL182418 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL180086 | — | Ki | > | 1000.0 | nM | - |