Assay Detail
Binding
CHEMBL827138
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Binding affinity against Alpha1 adrenergic receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Diaminopyrimidine and diaminopyridine 5-HT7 ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.44 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL363452 | — | — | 1 | 8.10 |
| CHEMBL183277 | — | — | 1 | 7.85 |
| CHEMBL183423 | — | — | 1 | 7.57 |
| CHEMBL182071 | — | — | 1 | 7.24 |
| CHEMBL184789 | — | — | 1 | 6.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL363452 | — | Ki | = | 8.0 | nM | 8.10 |
| CHEMBL183277 | — | Ki | = | 14.0 | nM | 7.85 |
| CHEMBL183423 | — | Ki | = | 27.0 | nM | 7.57 |
| CHEMBL182071 | — | Ki | = | 57.0 | nM | 7.24 |
| CHEMBL184789 | — | Ki | = | 379.0 | nM | 6.42 |