Assay Detail
Binding
CHEMBL827167
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Inhibition of [3H]DAMGO binding to rat whole brain Opioid receptor mu
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Morphiceptin analogues containing a dipeptide mimetic structure: an investigation on the bioactive topology at the mu-receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.85 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2113058 | — | — | 1 | 7.85 |
| CHEMBL267708 | — | — | 1 | 7.59 |
| CHEMBL2113060 | — | — | 1 | 6.75 |
| CHEMBL2113059 | — | — | 1 | 6.54 |
| CHEMBL191742 | — | — | 1 | 5.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2113058 | — | Ki | = | 14.1 | nM | 7.85 |
| CHEMBL267708 | — | Ki | = | 25.6 | nM | 7.59 |
| CHEMBL2113060 | — | Ki | = | 178.0 | nM | 6.75 |
| CHEMBL2113059 | — | Ki | = | 290.0 | nM | 6.54 |
| CHEMBL191742 | — | Ki | = | 3100.0 | nM | 5.51 |