Assay Detail
Binding
CHEMBL827905
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against human cathepsin K
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Rational design of potent and selective NH-linked aryl/heteroaryl cathepsin K inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.11 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL182956 | — | — | 1 | 9.70 |
| CHEMBL184514 | — | — | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL182956 | — | IC50 | = | 0.2 | nM | 9.70 |
| CHEMBL184514 | — | IC50 | = | 3.0 | nM | 8.52 |