Assay Detail
Binding
CHEMBL828055
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Inhibition of Matrix metalloprotease-1 in MMPi assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
A new development of matrix metalloproteinase inhibitors: twin hydroxamic acids as potent inhibitors of MMPs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.70 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL262397 | — | — | 1 | 6.40 |
| CHEMBL196647 | — | — | 1 | 5.00 |
| CHEMBL362651 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL262397 | — | IC50 | = | 397.0 | nM | 6.40 |
| CHEMBL196647 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL362651 | — | IC50 | > | 30000.0 | nM | - |