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Assay Detail

CHEMBL828218

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity for fatty acid amide hydrolase
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Fatty-acid amide hydrolase 1 (CHEMBL2243)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications.
Lambert DM, Fowler CJ.
J Med Chem (2005) 48 : 5059 -5087
PubMed 16078824 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 5 8.44 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL371831 1 9.00
CHEMBL422064 1 8.92
CHEMBL35925 1 8.64
CHEMBL191424 1 8.04
CHEMBL91417 1 7.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL371831 Ki = 1.0 nM 9.00
CHEMBL422064 Ki = 1.2 nM 8.92
CHEMBL35925 Ki = 2.3 nM 8.64
CHEMBL191424 Ki = 9.1 nM 8.04
CHEMBL91417 Ki = 25.0 nM 7.60