Assay Detail
Binding
CHEMBL828264
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Inhibition of [3H]CCPA binding to adenosine A1 receptor
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Development of spin-labeled probes for adenosine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 7.85 | 9.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL183 | 1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE [DPCPX] | — | 1 | 9.05 |
| CHEMBL607303 | — | — | 1 | 8.26 |
| CHEMBL607302 | — | — | 1 | 8.09 |
| CHEMBL607025 | — | — | 1 | 7.80 |
| CHEMBL37875 | — | — | 1 | 7.75 |
| CHEMBL288459 | — | — | 1 | 7.62 |
| CHEMBL2112962 | — | — | 1 | 7.39 |
| CHEMBL607024 | — | — | 1 | 6.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL183 | 1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE [DPCPX] | Ki | = | 0.9 | nM | 9.05 |
| CHEMBL607303 | — | Ki | = | 5.47 | nM | 8.26 |
| CHEMBL607302 | — | Ki | = | 8.23 | nM | 8.09 |
| CHEMBL607025 | — | Ki | = | 15.7 | nM | 7.80 |
| CHEMBL37875 | — | Ki | = | 18.0 | nM | 7.75 |
| CHEMBL288459 | — | Ki | = | 24.0 | nM | 7.62 |
| CHEMBL2112962 | — | Ki | = | 41.0 | nM | 7.39 |
| CHEMBL607024 | — | Ki | = | 160.0 | nM | 6.80 |