Assay Detail

CHEMBL828559

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Binding

Inhibitory concentration against hepatitis C virus helicase; range 0.6-0.7

ChEMBL ↗

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Target

NS3 (CHEMBL1293269) ↗

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Primary target NS3

CHEMBL1293269

Anchored from Assay target.

Protein identity NS3

Disease frame Disease evidence pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Hepacivirus hominis
Confidence	9 — Direct single protein target
Curated By	Expert

Target

NS3 (CHEMBL1293269) ↗

Type	SINGLE PROTEIN
Organism	Hepatitis C virus

Publication

Control of hepatitis C: a medicinal chemistry perspective.

Gordon CP, Keller PA.
J Med Chem (2005) 48 : 1 -20
PubMed 15633995 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.16	6.16

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL422	TRIFLUOPERAZINE	4.0	1	6.16

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL422	TRIFLUOPERAZINE	IC50	=	700.0	nM	6.16