Assay Detail
Binding
CHEMBL828767
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]mesulergine binding to rat 5-hydroxytryptamine 2C receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Novel atypical antipsychotic agents: rational design, an efficient palladium-catalyzed route, and pharmacological studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.12 | 8.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL179557 | — | — | 1 | 8.42 |
| CHEMBL178564 | — | — | 1 | 7.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL179557 | — | Ki | = | 3.8 | nM | 8.42 |
| CHEMBL178564 | — | Ki | = | 15.0 | nM | 7.82 |