Assay Detail
Binding
CHEMBL828924
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against human Coagulation factor X
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and structure-activity relationships of novel selective factor Xa inhibitors with a tetrahydroisoquinoline ring.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.56 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL195428 | — | — | 1 | 7.72 |
| CHEMBL539053 | DX-9065A HYDROCHLORIDE HYDRATE | — | 1 | 7.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL195428 | — | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL539053 | DX-9065A HYDROCHLORIDE HYDRATE | Ki | = | 41.0 | nM | 7.39 |