Assay Detail
Binding
CHEMBL829071
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Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 2
45
Total Activities
45
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Somatostatin receptor 1 selective analogues: 2. N(alpha)-Methylated scan.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 45 | 7.94 | 8.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL442494 | — | — | 1 | 8.64 |
| CHEMBL262379 | — | — | 1 | 7.80 |
| CHEMBL408338 | — | — | 1 | 7.37 |
| CHEMBL404819 | — | — | 1 | - |
| CHEMBL409653 | — | — | 1 | - |
| CHEMBL262551 | — | — | 1 | - |
| CHEMBL410144 | — | — | 1 | - |
| CHEMBL412473 | — | — | 1 | - |
| CHEMBL268205 | — | — | 1 | - |
| CHEMBL413442 | — | — | 1 | - |
| CHEMBL410048 | — | — | 1 | - |
| CHEMBL440618 | — | — | 1 | - |
| CHEMBL216789 | — | — | 1 | - |
| CHEMBL428295 | — | — | 1 | - |
| CHEMBL440066 | — | — | 1 | - |
| CHEMBL384195 | — | — | 1 | - |
| CHEMBL384855 | — | — | 1 | - |
| CHEMBL413419 | — | — | 1 | - |
| CHEMBL406197 | — | — | 1 | - |
| CHEMBL427658 | — | — | 1 | - |
| CHEMBL407051 | — | — | 1 | - |
| CHEMBL411860 | — | — | 1 | - |
| CHEMBL436887 | — | — | 1 | - |
| CHEMBL268448 | — | — | 1 | - |
| CHEMBL425465 | — | — | 1 | - |
| CHEMBL265120 | — | — | 1 | - |
| CHEMBL438576 | — | — | 1 | - |
| CHEMBL264839 | — | — | 1 | - |
| CHEMBL437905 | — | — | 1 | - |
| CHEMBL414717 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL442494 | — | IC50 | = | 2.3 | nM | 8.64 |
| CHEMBL262379 | — | IC50 | = | 16.0 | nM | 7.80 |
| CHEMBL408338 | — | IC50 | = | 43.0 | nM | 7.37 |
| CHEMBL268205 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL429709 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL412473 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL410144 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL262551 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL409653 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL404819 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL411002 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL414692 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL385811 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL262790 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL415144 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL415143 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL386023 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL410428 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL408611 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL406559 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL444639 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL439263 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL407125 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL414716 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL427658 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL414717 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL437905 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL264839 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL438576 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL265120 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL425465 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL268448 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL436887 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL411860 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL407051 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL413442 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL406197 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL413419 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL384855 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL384195 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL440066 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL428295 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL216789 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL440618 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL410048 | — | IC50 | > | 1000.0 | nM | - |