Assay Detail
Functional
CHEMBL829173
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration to antagonise accessory gene regulator C4 of Staphylococcus aureus
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Staphylococcus aureus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Receptor-histidine kinase AgrC (CHEMBL4726) ↗| Type | SINGLE PROTEIN |
| Organism | Staphylococcus aureus |
Publication
Virulence regulation and quorum sensing in staphylococcal infections: competitive AgrC antagonists as quorum sensing inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.89 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL426697 | YSTCYFIM | — | 1 | 7.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL426697 | YSTCYFIM | EC50 | = | 13.0 | nM | 7.89 |