Assay Detail
Binding
CHEMBL829362
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against Protein tyrosine phosphatase 1B
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Tyrosine-protein phosphatase non-receptor type 1 (CHEMBL335) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structure-based design of protein tyrosine phosphatase-1B inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.61 | 5.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL193233 | — | — | 1 | 5.61 |
| CHEMBL190801 | — | — | 1 | - |
| CHEMBL190970 | — | — | 1 | - |
| CHEMBL190833 | — | — | 1 | - |
| CHEMBL191219 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL193233 | — | IC50 | = | 2470.0 | nM | 5.61 |
| CHEMBL190801 | — | IC50 | = | 1608000.0 | nM | - |
| CHEMBL190970 | — | IC50 | = | 203000.0 | nM | - |
| CHEMBL190833 | — | IC50 | = | 138000.0 | nM | - |
| CHEMBL191219 | — | IC50 | = | 132000.0 | nM | - |