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Assay Detail

CHEMBL829437

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against Platelet-derived growth factor receptor kinase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis of selective SRPK-1 inhibitors: novel tricyclic quinoxaline derivatives.
Székelyhidi Z, Pató J, Wáczek F, Bánhegyi P, Hegymegi-Barakonyi B, Erös D, Mészáros G, Hollósy F, Hafenbradl D, Obert S, Klebl B, Kéri G, Orfi L.
Bioorg Med Chem Lett (2005) 15 : 3241 -3246
PubMed 15925511 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.05 6.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL69644 1 6.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL69644 IC50 = 900.0 nM 6.05