Compound Detail
CHEMBL69644
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Basic Information
| ChEMBL ID | CHEMBL69644 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NZFXNLXEQRQPJT-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
256.3
MW (Da)
4.45
ALogP
2
HBA
0
HBD
25.8
PSA (Ų)
0.47
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-derived growth factor receptor CHEMBL2096980 | IC50 | 6.05 | 6.05 | 900.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 6.05 | 6.05 | 900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Platelet-derived growth factor receptor | IC50 | = | 900.0 | nM | 6.05 | Inhibitory activity against platelet-derived growth factor receptor tyrosine kin... | 8667360 |
| Unchecked | IC50 | = | 900.0 | nM | 6.05 | Inhibitory activity against Platelet-derived growth factor receptor kinase | 15925511 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8667360 | 10.1021/jm950727b | Platelet-derived growth factor receptor | 1 |
| 15925511 | 10.1016/j.bmcl.2005.04.064 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine