Assay Detail
Binding
CHEMBL829633
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards 5-HT1A receptor from porcine cortical membranes using [3H]8-OH-DPAT
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 7.33 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL182652 | — | — | 1 | 8.00 |
| CHEMBL362101 | — | — | 1 | 7.62 |
| CHEMBL184993 | — | — | 1 | 7.57 |
| CHEMBL182379 | — | — | 1 | 7.48 |
| CHEMBL183871 | — | — | 1 | 7.34 |
| CHEMBL184383 | — | — | 1 | 6.89 |
| CHEMBL59725 | — | — | 1 | 6.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL182652 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL362101 | — | Ki | = | 24.0 | nM | 7.62 |
| CHEMBL184993 | — | Ki | = | 27.0 | nM | 7.57 |
| CHEMBL182379 | — | Ki | = | 33.0 | nM | 7.48 |
| CHEMBL183871 | — | Ki | = | 46.0 | nM | 7.34 |
| CHEMBL184383 | — | Ki | = | 130.0 | nM | 6.89 |
| CHEMBL59725 | — | Ki | = | 360.0 | nM | 6.44 |