Assay Detail
Binding
CHEMBL829939
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required for inhibition of 5-hydroxytryptamine 2 receptor using [3H]ketanserin as the radioligand
5
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.98 | 8.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1729 | CISAPRIDE | 4.0 | 1 | 8.21 |
| CHEMBL295155 | — | — | 2 | 5.75 |
| CHEMBL2448165 | — | — | 1 | - |
| CHEMBL3085015 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1729 | CISAPRIDE | IC50 | = | 6.1 | nM | 8.21 |
| CHEMBL295155 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL2448165 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL295155 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3085015 | — | IC50 | > | 10000.0 | nM | - |