Assay Detail
Binding
CHEMBL829960
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]CPP binding to rat N-methyl-D-aspartic acid receptor 2A
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Glutamate receptor ionotropic, NMDA 2A (CHEMBL310) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Development of a three-dimensional model for the N-methyl-D-aspartate NR2A subunit.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.00 | 7.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29811 | CGP-37849 | — | 1 | 7.46 |
| CHEMBL39664 | SELFOTEL | 2.0 | 1 | 7.02 |
| CHEMBL431029 | — | — | 1 | 6.96 |
| CHEMBL71898 | — | — | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29811 | CGP-37849 | IC50 | = | 35.0 | nM | 7.46 |
| CHEMBL39664 | SELFOTEL | IC50 | = | 95.0 | nM | 7.02 |
| CHEMBL431029 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL71898 | — | IC50 | = | 290.0 | nM | 6.54 |