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Assay Detail

CHEMBL829973

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uM
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Expert

Target

Adenosine receptor A1 (CHEMBL226)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

"Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists.
Perreira M, Jiang JK, Klutz AM, Gao ZG, Shainberg A, Lu C, Thomas CJ, Jacobson KA.
J Med Chem (2005) 48 : 4910 -4918
PubMed 16033270 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.56 5.56

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL188592 1 5.56

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL188592 Ki = 2730.0 nM 5.56