Assay Detail
Binding
CHEMBL829992
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]yohimbine binding to Adrenergic receptor alpha 2 receptor from rat brain cortex
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.51 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL189890 | — | — | 1 | 5.77 |
| CHEMBL193182 | — | — | 1 | 5.50 |
| CHEMBL189384 | — | — | 1 | 5.44 |
| CHEMBL191226 | — | — | 1 | 5.33 |
| CHEMBL364530 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL189890 | — | Ki | = | 1710.0 | nM | 5.77 |
| CHEMBL193182 | — | Ki | = | 3140.0 | nM | 5.50 |
| CHEMBL189384 | — | Ki | = | 3650.0 | nM | 5.44 |
| CHEMBL191226 | — | Ki | = | 4680.0 | nM | 5.33 |
| CHEMBL364530 | — | Ki | > | 100000.0 | nM | - |