Assay Detail
Binding
CHEMBL830125
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Inhibitory concentration against DPP-II [Quiescent cell proline dipeptidase] or DPP-VII
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.41 | 4.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL77538 | — | — | 1 | 4.58 |
| CHEMBL369883 | — | — | 1 | 4.50 |
| CHEMBL307636 | — | — | 1 | 4.40 |
| CHEMBL98408 | — | — | 1 | 4.16 |
| CHEMBL362018 | — | — | 1 | - |
| CHEMBL142703 | VILDAGLIPTIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL77538 | — | IC50 | = | 26520.0 | nM | 4.58 |
| CHEMBL369883 | — | IC50 | = | 31259.0 | nM | 4.50 |
| CHEMBL307636 | — | IC50 | = | 39873.0 | nM | 4.40 |
| CHEMBL98408 | — | IC50 | = | 68985.0 | nM | 4.16 |
| CHEMBL362018 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL142703 | VILDAGLIPTIN | IC50 | > | 100000.0 | nM | - |