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Assay Detail

CHEMBL830145

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of DAMGO (Tyr-[D-Ala]-Gly-[NMe-Phe]-Gly-ol) binding to rat brain opioid receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Mu-type opioid receptor (CHEMBL270)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Ligand-based prediction of active conformation by 3D-QSAR flexibility descriptors and their application in 3+3D-QSAR models.
Martinek TA, Otvös F, Dervarics M, Tóth G, Fülöp F.
J Med Chem (2005) 48 : 3239 -3250
PubMed 15857130 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.58 7.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL163334 1 7.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL163334 Ki = 26.3 nM 7.58