Assay Detail
Binding
CHEMBL830231
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Binding affinity for T-cell Protein tyrosine phosphatase (TCPTP)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Tyrosine-protein phosphatase non-receptor type 2 (CHEMBL3807) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.62 | 4.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184444 | — | — | 1 | 4.72 |
| CHEMBL186337 | — | — | 1 | 4.52 |
| CHEMBL117869 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184444 | — | Ki | = | 19200.0 | nM | 4.72 |
| CHEMBL186337 | — | Ki | = | 30000.0 | nM | 4.52 |
| CHEMBL117869 | — | Ki | = | 164000.0 | nM | - |