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Assay Detail

CHEMBL830240

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition constant against human cathepsin H using L-Arg-b-naphthalamide
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Pro-cathepsin H (CHEMBL2225)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Acyclic cyanamide-based inhibitors of cathepsin K.
Barrett DG, Deaton DN, Hassell AM, McFadyen RB, Miller AB, Miller LR, Payne JA, Shewchuk LM, Willard DH, Wright LL.
Bioorg Med Chem Lett (2005) 15 : 3039 -3043
PubMed 15896958 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 9.34 9.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL371420 1 9.34
CHEMBL189149 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL371420 Ki = 0.46 nM 9.34
CHEMBL189149 Ki > 13000.0 nM -